All horses developed intrapulmonary shunt during anaesthesia, but shunt was significantly greater (13 +/- 5%) when O2-rich gas was delivered compared with air breathing (5 +/- 2% p = 0.013). Breathing O2-rich gas was associated with a decreased respiratory rate (p = 0.015) increased PaCO2 (p & amp amp amp amp amp amp amp amp amp amp amp lt 0.001) and increased PaO2 (p = 0.004) compared with breathing air. Respiratory and haemodynamic variables and the distribution of ventilation-perfusion (VA/Q) ratios (using the multiple inert gas elimination technique) were determined in the standing conscious horse (baseline) after sedation and during anaesthesia. The alternative treatment was delivered at the second anaesthetic. One of two, randomly allocated inspired gas treatments was provided: either i) room air (fractional concentration of inspired O2 = 0.21) provided throughout anaesthesia or ii) an O2-rich gas mixture (FIO2 = & amp amp amp amp amp amp amp amp amp amp amp gt 0.95) for 15 minutes, followed by room air. After endotracheal intubation and positioning in left lateral recumbency, animals were allowed to breathe spontaneously. Horses were anaesthetized on two occasions with tiletamine-zolazepam after pre-anaesthetic medication with acepromazine, romifidine and butorphanol. Study design Randomized, cross-over experimental study. Six healthy standard bred trotters (age range 3-12 years mass range 423-520 kg), four geldings and two mares. To compare pulmonary function and gas exchange in anaesthetized horses during and after breathing either O2-rich gas mixtures or air.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |